Cell Cycle and Genome Instability

PUBLICATIONS

• Pu, W., Zhang, H., Qin, P., and Deng, L.* (2021) Nuclear envelope integrity, DNA replication, damage repair and genome stability. Genome Instability & Disease, 1,

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• Sun, K., Li, L., Ma, L., Zhao, Y., Deng, L., Wang, H., and Sun, H. (2020) Msuite: A High-Performance and Versatile DNA Methylation Data-Analysis Toolkit. Patterns, 1:100127, DOI:https://doi.org/10.1016/j.patter.2020.100127

• Dong, Y., Lee, Y., Cui, K., He, M., Wang, B., Bhattacharjee, S., Zhu, B., Yago, T., Zhang, K., Deng, L., Ouyang, K., Wen, A., Cowan, D., Song, K., Yu, L., Brophy, M., Liu, X., Wylie-Sears, J., Wu, H., Wong, S., Cui, G., Kawashima, Y., Matsumoto, H., Kodera, Y., Wojcikiewicz, R., Srivastava, S., Bischoff, J., Wang, D., Ley, K., and Chen H. (2020). Epsin-mediated degradation of IP3R1 fuels atherosclerosis. Nature Communications, 11(1):3984. doi: 10.1038/s41467-020-17848-4. PMID: 32770009

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• Deng, L., Wu, R.A., Sonneville, R., Kochenova, O.V., Labib, K., Pellman, D., and Walter, J.C. (2019). Mitotic CDK promotes replisome disassembly, fork collapse, and complex DNA rearrangements. Molecular Cell, 73(5):915-929.e6. PMID: 30849395.

       **Recommended by F1000 in Cell Biology

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• Wu, R.A., Semlow, D.R., Kamimae-Lanning, A.N., Kochenova, O.V., Chistol, G., Hodskinson, M.R., Amunugama, R., Sparks, J.L., Wang, M., Deng, L., Mimoso, C.A., Patel, K.J., and Walter, J.C. (2019). TRAIP is a master regulator of cross-link repair and replisome stability. Nature, doi: 10.1038/s41586-019-1002-0. PMID: 30842657.

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• Deng, L., Lee, M.E. Schutt K.L., and Moseley, J.B. (2017). Phosphatases generate signal specificity downstream of Ssp1 kinase in fission yeast. Molecular and Cellular Biology 37:e00494-16.doi: 10.1128/MCB.00494-16. PMID: 28223368.

       **Featured article in MCB, May 2017.

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• Wu, Y., Dong, Y., Duan, S., Zhu, D., and Deng, L. (2017). Editorial: metabolic syndrome, inflammation, and cancer. Mediators of Inflammation, doi.org/10.1155/2017/8259356.

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• ​Zurawel, A.A., Kabeche, R., DiGregorio, S.E., Deng, L., Menon, K.M., Opalko, H., Duennwald, M.L., Moseley, J.B., and Supattapone, S. (2016). CAG expansions are genetically stable and form nontoxic aggregates in cells lacking endogenous polyglutamine proteins. mBio 7, doi: 10.1128/mBio.01367-16. PMID: 27677791.

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• Dong, Y., Cai, X., Wu, Y., Liu, Y., Deng, L., and Chen, H. (2016). Insights from genetic model systems of retinal degeneration: role of Epsins in retinal angiogenesis and VEGFR2 signaling. Journal of Nature and Science 3, (1):e281.

• Dong, Y., Fernandes, C., Liu, Y., Wu, Y., Wu, H., Brophy, M.L., Deng, L., Song, K., Wen, A., Wong, S., Yan, D., Towner, R., and Chen, H. (2016). Role of endoplasmic reticulum stress signaling in diabetic endothelial dysfunction and atherosclerosis. Diabetes & Vascular Disease Research. doi: 10.1177/1479164116666762.

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• Tang, C.,# Deng, L.,# Chang D., Chen S., Wang, X., and Kang, Z. (2016). TaADF3, actin-depolymerizing factor, negatively modulates wheat resistance against Puccinia striiformis. Frontiers in Plant Science 6:1214 doi: 10.3389/fpls.2015.01214. PMID: 26834758. (#co-first author)

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• Liu, M., Peng, Y., Li, H., Deng, L., Wang, X., and Kang, Z. (2016). TaSYP71, a Qc-SNARE, Contributes to Wheat Resistance against Puccinia striiformis f. sp. tritici. Frontiers in Plant Science 6:544. doi: 10.3389/fpls.2016.00544. PMID: 27148348.

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• Kettenbach, A., Deng, L., Wu, Y., Baldissard, S., Gerber, S., and Moseley, J.B. (2015). Quantitative phosphoproteomics reveals substrates and mechanisms for the fission yeast DYRK kinase Pom1. Molecular & Cellular Proteomics 14, 1275-87. PMID: 26834758.

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• Deng, L., Baldissard, S., Kettenbach, A.N., Gerber, S.A., and Moseley, J.B. (2014). Dueling kinases regulate cell size at division through the SAD kinase Cdr2. Current Biology 24, 428-433. PMID: 24508166.

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• Deng, L., Kabeche, R., Wang, N., Wu, J.Q., and Moseley, J.B. (2014). Megadalton node assembly by binding of Skb1 to the membrane anchor Slf1. Molecular Biology of the Cell 25, 2660-2668. PMID: 25009287.

       **A highlight from MBoC Selection; Highlighted in October 2014 ASCB Newsletter

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• Wang, X., Wang, X., Deng, L., Chang, H., Dubcovsky, J., Feng, H., Han, Q., Huang, L., and Kang Z. (2014). Wheat TaNPSN SNARE homologues are involved in vesicle-mediated resistance to stripe rust (Puccinia striiformis f. sp. tritici). Journal of Experimental Botany 65, 4807–4820. PMID: 24963004.

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• Deng, L., and Moseley, J.B. (2013). Compartmentalized nodes control mitotic entry signaling in fission yeast. Molecular Biology of the Cell 24, 1872-1881. PMID: 23615447.

       **A highlight from MBoC Selection; Highlighted in July 2013 ASCB Newsletter

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• 邓麟, 顾立伟, 王锋钢, 王经民. (2012). 抗艾滋病药物的评价与预测模型. 纯粹数学与应用数学 28, 275-284.

• Wang, X., Tang, C., Deng, L., Cai, G., Liu, X., Liu, B., Han, Q., Buchenauer, H., Wei, G., Han, D., Huang, L., and Kang, Z. (2010). Characterization of a pathogenesis-related thaumatin-like protein gene TaPR5 from wheat induced by stripe rust fungus. Physiologia Plantarum 139, 27-38. PMID: 20059734.

• Xia, N., Zhang, G., Liu, X., Deng, L., Cai, G., Zhang, Y., Wang, X., Zhao, J., Huang, L., and Kang, Z. (2010). Characterization of a novel wheat NAC transcription factor gene involved in defense response against stripe rust pathogen infection and abiotic stresses. Molecular Biology Reports 37, 3703-3712. PMID: 20213512.

• 邓麟#,王晓杰#, 刘新颖, 蔡高磊, 汤春蕾, 魏国荣, 黄丽丽, 康振生. (2010). 条锈菌诱导的小麦TaHin1的克隆与表达特征分析. 中国农业科学 43, 2403-2409. (#co-first author)

• 蔡高磊, 王晓杰, 刘丹, 邓麟, 刘新颖, 汤春蕾, 赵杰, 魏国荣, 黄丽丽, 康振生. (2010). 条锈菌诱导的小麦TaOZR 的克隆及特征分析. 中国农业科学 43, 2403-2409.

• 刘新颖, 王晓杰, 薛杰, 夏宁, 邓麟, 蔡高磊, 汤春蕾, 魏国荣, 黄丽丽, 康振生. (2010). 小麦钙调素新亚型TaCaM5 的克隆及表达分析. 作物学报. 36, 953−960.

• 邓麟, 曹金锁, 王秦虎, 常伟平. (2007). 植物化感作用研究进展. 陕西农业科学 4, 81-83.

• 王秦虎, 邓麟, 韩翠芹. (2007). 人工神经网络预测蛋白质二级结构的编码技术综述. 陕西农业科学 6, 109-112.